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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight loss in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to shed pounds can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err to the side of caution and permit the FDA do its job and demand some study be done so your public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on his or her medications.

    Researchers found that participants using this drug for the year, dropped a few pounds within four weeks and have kept the body weight off during the entire 56 weeks of the study. Contrave is often a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which might be made up of multiple active ingredient, which might make them far better and safer.

    Combo-pilling may be the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular will be the fact that as of right now there are no long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise hypertension and heart rate, and must not be used in individuals with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and heart rate and must not be used in patients with uncontrolled high blood pressure, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

    Other people who must avoid using Contrave are patients struggling with bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave mustn't be prescribed for girls who are pregnant or attempting to become pregnant.